Everything You Need To Know In-Depth About Sildenafil

Sildenafil citrate is a salt used as a PDE5 blocker that intends to cure the problem of erectile dysfunction among men. This medicine is found in various forms such as liquid, tablet, and intravenous. But without the assistance of medical professionals, patients should not take intravenous medicine. People can purchase this medicine both in generic form and branded form. Viagra and Revatio are the names of reputed brands of sildenafil. 

Use of sildenafil citrate

They feel the effect of PDE5 inhibitors by consuming several types of medicines such as Fildena, Cenforce, Malegra, Kamagra, etc. This active substance gives strength to the men to erect hard for a long time. But this medicine can be effective only if patients are sexually excited. After taking this medicine, the couple can enjoy uninterrupted sex for up to 4 hours.

How does sildenafil citrate work in the body?

An inadequate supply of blood in the penis causes problems with erection. The penis releases the PDE-5 enzyme that impedes the bloodstream flow in the penis by not storing cyclic guanosine monophosphate, and it leads to difficulty in penetration.

But sildenafil citrate acts against PDE5 and allows cGMP accumulation in the corpus cavernosum. As a result, nitric oxide, named chemical messenger, gets released, and it helps relax the muscles of the penis. That ultimately induces a brutal, prolonged erection.

How to take sildenafil citrate?

When deciding to take this medicine, patients have to restrict themselves from drinking excessive alcohol or smoking. If you want to take this tablet along with food to avoid an empty stomach, you may take low-fat meals. But to get the best result, try to take this medicine on an empty stomach.

You have to swallow this pill and sufficient water, and you have to take this pill mandatorily at least 30-60 minutes earlier than foreplay with your partner. Since the CYP3A4 inhibitor metabolizes this medicine in the liver, patients should not drink grapefruit juice due to the presence of CYP3A4.

Dosage of sildenafil citrate

This medicine is available in different strengths, from 50 Mg-Sildenafil 100 mg. Patients do not have any idea about dosage adjustment. For this purpose, medical assistance is very much needed. Patients are permitted to take only one pill within 24 hours. Even they have to continue to take this pill until the doctor tells them to stop it.

If you ever feel that you have taken a larger quantity for lack of your knowledge, go to the doctor immediately to treat side effects like trouble breathing, itching, infertility, sleepiness, and many more.

Patients should take this medicine regularly at a fixed time. But if you ever fail to do so, take it whenever possible. But make sure that you will take a missed dose when you have enough time left for taking a new dose. Otherwise, skip taking the failed dose and choose only the new dose. Never take a double dose to adjust the previous medicine.


After taking this pill, patients may be affected by moderate to serious side effects. Patients do not need to go to the doctor to treat common or mild side effects such as muscle pain, stomach pain, dizziness, nosebleeds, or diarrhea. But medical assistance is highly required to prevent serious side effects such as priapism, painful urination, swelling of the face, throat, and infertility.

Who cannot take Sildenafil citrate?

Children below 18 years, women, and pets should avoid the vicinity of this medicine.

Patients suffering from co-morbidity like diabetes and cardiovascular diseases such as irregular heartbeat, and stroke, should not take this medicine, and it proves fatal for them. Apart from these, those who suffer from the problem of liver disease, kidney disease, thyroid, and hypertension should be careful about taking it.

If patients experience a painful erection after 4 hours, they must go to the doctor immediately. Otherwise, the tissue of the penis gets damaged, and patients become impotent permanently.

Patients who have an angular or deformed penis, fibrosis, or blood cell disorders such as sickle cell anemia or myeloma should not consume this medicine. They have more inclination to priapism.

Patients who have a severe bleeding disorder such as a peptic ulcer or active ulcer need to avoid this medicine.

Drug interactions

  • Amlodipine
  • Alpha-blockers like doxazosin, tamsulosin
  • Hepatitis C vaccine
  • Ritonavir, saquinavir
  • Nitroglycerine, nitroprusside

How to store it?

This medicine should store in a cold, clean, and dark place. After opening this original package, keep it in an airtight container, and it should store below 30 degrees c temperature.

Why should you buy sildenafil citrate from Medicationvilla.com?

This medicine is available in several medicine stores. But make sure that you buy it from a central place. You can choose an internet-based medicine store Medicationvilla for this purpose. That is one of the trusted, legitimate druggist stores in the World. This company has instilled faith among people for its excellent service, packaging quality, quick delivery, and selling of genuine products. 

This company sells only genuine products and has tied up with branded raw material stores. So they never sell adulterated products. Every customer wants the best product at a reasonable price. For this reason, they suggest you purchase products using a credit card or debit card. 

It helps them to have some additional discounts and some lucrative offers. The damaged product causes several problems and is not fruitful to treat issues. For this reason, this online store packages the product using the best quality material so that they can deliver your item in an indefensible manner. If customers are not satisfied after receiving your product, they can return it in 30 days.

They understand your urgency for your ordered item. For this reason, they try to deliver your product before the stipulated time given by them. This company sells over-the-counter products and branded medicines. So if after taking medicine, patients face any problem, they are not responsible for that. So before placing an order, make sure that you have a valid prescription and go through the norms given by this company.

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